Nocturnal Sleep Dynamics Identify Narcolepsy Type 1
نویسندگان
چکیده
منابع مشابه
Manipulation of skin temperature improves nocturnal sleep in narcolepsy.
OBJECTIVE Besides excessive daytime sleepiness, disturbed nocturnal sleep is a major complaint of patients with narcolepsy. Previously, alterations in skin temperature regulation in narcoleptic patients have been shown to be related to increased sleepiness. This study tests the hypothesis that direct control of nocturnal skin temperature might be applied to improve the disturbed sleep of narcol...
متن کاملNocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency.
IMPORTANCE Narcolepsy, a disorder associated with HLA-DQB1*06:02 and caused by hypocretin (orexin) deficiency, is diagnosed using the Multiple Sleep Latency Test (MSLT) following nocturnal polysomnography (NPSG). In many patients, a short rapid eye movement sleep latency (REML) during the NPSG is also observed but not used diagnostically. OBJECTIVE To determine diagnostic accuracy and clinica...
متن کاملHypocretin/orexin, sleep and narcolepsy.
The discovery that hypocretins are involved in narcolepsy, a disorder associated with excessive daytime sleepiness, cataplexy and unusually rapid transitions to rapid-eye-movement sleep, opens a new field of investigation in the area of sleep control physiology. Hypocretin-1 and -2 (also called orexin-A and -B) are newly discovered neuropeptides processed from a common precursor, preprohypocret...
متن کاملGrey zone between narcolepsy type 1 and type 2.
Dear Editor, The third International Classification of Sleep Disorders (ICSD-3) defines narcolepsy as patients with periods of sleep attacks or excessive daytime sleepiness. Neurophysiology tests with unremarkable polysomnography and positive Multiple Sleep Latency Test scores establish the diagnosis of narcolepsy1. The difficulties in the differential diagnosis include secondary causes of exce...
متن کاملNarcolepsy type 1 and hypersomnia associated with a psychiatric disorder show different slow wave activity dynamics.
The aim of the study was to compare electrophysiological parameters of night sleep in narcolepsy type 1 and hypersomnia associated with a psychiatric disorder. Fortyfour patients: 15 with narcolepsy type 1, 14 with hypersomnia associated with a psychiatric disorder and 15 age- and sex-matched controls participated in the study. The study subjects filled in the Athens Insomnia Scale (AIS) and th...
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ژورنال
عنوان ژورنال: Sleep
سال: 2015
ISSN: 1550-9109,0161-8105
DOI: 10.5665/sleep.4908